At Salvia, we have developed a paper-thin implant for people with migraine. The implant is a flexible bioelectronic foil placed just under the skin, near the nerves associated with migraine. By sending mild electrical pulses through the foil, we aim to effectively calm the nerves and prevent and relieve migraine symptoms.  

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"I have my life back," said our first clinical trial patient, a woman from Australia who has suffered from debilitating headaches since the age of 14. "This little device allows me to regain control of my life and be fully involved with my kids."

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Salvia’s device is not yet approved for commercial use. We make no claims about safety or effectiveness.

Our nervous system transmits tiny electrical signals that coordinate our body's functions. However, in chronic diseases such as migraine, this communication can become disrupted. Bioelectronic medical devices can play a vital role in restoring this balance by gently modulating nerve signals, much like a pacemaker for the heart, but specifically designed for the nervous system. This is called neuromodulation.

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Neuromodulation is not new; it has a well-documented history dating back to the early 1960s. This therapeutic approach has been successfully used to treat individuals suffering from various neurological conditions, including Parkinson's disease and epilepsy.

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Salvia's expertise is in helping people with migraine and cluster headache. Our bioelectronic foil, designed specifically for the anatomy of the head, can be implanted in the front or back of the head, just under the skin, providing a safe and direct connection to the nerves associated with migraine. Through our neuromodulation therapy, we aim to restore balance to the brain by calming these nerves.

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Our goal is to create more 'crystal clear days' for people with migraine.

Crystal clear days are days without pain or brain fog. These crystal clear days symbolize the moments when patients fully regain their quality of life, increase their productivity and actively participate in society.

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• ^{Yilong Zheng, Christopher Weiyang Liu, Diana Xin Hui Chan, Damian Wen Kai Ong, Justin Rui Xin Ker, Wai Hoe Ng, Kai Rui Wan, Neurostimulation for Chronic Pain: A Systematic Review of High-Quality Randomized Controlled Trials With Long-Term Follow-Up, Neuromodulation: Technology at the Neural Interface, Volume 26, Issue 7, 2023, Pages 1276-1294, ISSN 1094-7159}
• ^{M. D. Johnson et al., "Neuromodulation for Brain Disorders: Challenges and Opportunities," in IEEE Transactions on Biomedical Engineering, vol. 60, no. 3, pp. 610-624, March 2013, doi: 10.1109/TBME.2013.2244890}

Patients can manage their own migraine treatment with a small, portable device called "MySalvia device". This external device interfaces with the implant to activate the neuromodulation therapy, tailored to the patient's needs.

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In addition to the MySalvia device, patients will be able to monitor their progress and access personalized migraine treatment through the MySalvia app.